1/20/2020

What is NAD+?

Product Name
β-Nicotinamide adenine dinucleotide(NAD)
Molecular Formula
C21H27N7O14P2
Molecular Weight
663.4
CAS Number
53-84-9
Specifications
98%
Appearance/color
White to yellow powder
Benefits
Cell regenerator, Anti-aging, Health the brain
Dosage
10mg to 50mg
Storage
Below 8for long time storage


NAD is short for nicotinamide adenine dinucleotide.
It is a coenzyme and exists in NAD+ form and NADH form.
Here we talk about NAD+.
Now, there is a small power plant in every cell of your body. It is called the mitochondria.
Mitochondria are the source of all energy in the body. From lifting weights, blinking, digesting food to the heartbeat, everything relies on mitochondria.
NAD+ is the primary source to keep mitochondria activity.
When we were young, our bodies were full of NAD+. We get all the NAD+ we want.
But as we age, our NAD+ levels begin to fall like stones. Every 20 years, your NAD+ level drops by 50%.
Mechanism of NAD+Aging

NAD does not affect the body directly. It just helps your cells work better.
NAD works by transferring electrons from one place to another. Therefore, you can think of each NAD coenzyme as a shuttle bus that brings particles to the mitochondria.
The more shuttle buses you have, the more electrons enter the mitochondria. The chemical reactions caused by the transmission can provide energy to cells and keep them vibrant.
Mitochondria will process fewer nutrients and reactions if there are not many NAD shuttle buses. As a result, your cells begin to age and die. Aging is coming.
Besides, the "longevity gene" Sirtuins is a family of seven proteins. These proteins control aging through cellular health. Sirtuins can only work in the presence of NAD+. If sirtuins are the CEO, NAD+ is the salary for the CEO and employees. The company cant work well without enough NAD+.

Nicotinamide Adenine Dinucleotide Supplements

Hypodermic injection
In mice, NAD+ injections have been successful.
In humans, NAD+ by intravenous injection is becoming more popular in the clinic, although it costs more than $1,000 a day and requires patients to receive intravenous drip for 8 hours.
NAD+ in capsule
Scientific tests showed that intraperitoneal injections of Nam, NAD+, and NADH significantly increased the urine output of Nam and its metabolites. Oral Nam and NAD+ have the same effect.
Sublingual delivery
The sublingual capillaries can directly absorb NMN, NR, NAD+, because of these products’ small molecular weight and excellent hydrophilicity. This dose is called sublingual transmission.

NAD+ and NADH
NAD has two forms: NAD+ and NADH. The oxidized form is NAD+, and the reduced way is NADH.
Lets go back to the shuttle bus metaphor, and we can look at them as full of electron passengers bus and empty buses.
NAD and NADH can both activate a variety of enzymes.
NAD and NADH transform into each other in many metabolic activities. In some metabolic reactions, NAD is an essential catalyst while NADH is a useful by-product. However, in other reactions, they exchange status.

In cells, most oxidations are accomplished by the removal of hydrogen atoms. Each molecule of NAD+ can acquire two electrons, or we say two electrons reduce it. However, only one proton accompanies the reduction. The other proton produced as two hydrogen atoms are removed from the molecule being oxidized is liberated into the surrounding medium.The reaction is :NAD+ + 2H -> NADH + H+



NAD+ Benefits
· Increases cellular metabolism and energy production
· Maintains healthy mitochondria
· helps enhance brain functions
· Promotes mobile repair
· promote healthy aging to make you look good

Cima Science's NAD+

https://cimasci.com/products/nad-powder/





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