What is Oxaloacetic acid(OAA)?
Oxaloacetic acid is a dicarboxylic acid that is a substrate for the enzymes malate dehydrogenase and oxalacetate decarboxylase when the oxaloacetic acid is in its anionic form oxaloacetate.
Oxaloacetic acid, in the form of its conjugate base oxaloacetate, is a metabolic intermediate in many processes that occur in animals.
Chemical profile
Chinese name:草酰乙酸
English name:Oxaloacetic acid
Other name:OAA, oxobutanedioic acid, Oxalacetic acid,benaGene, Ketosuccinic acid
2-Oxosuccinic acid, Ketosuccinic acid, Oxaloacetate,3-carboxy-3-oxopropanoic acid
CAS No.:328-42-7
Molecular Formula: C4H4O5
Molecular Weight:132.1
Specification:98%
Appearance: White crystalline powder
Applications: Dietary supplements, medicines, skincare cosmetics
Functions of Oxaloacetic acid
Oxaloacetic acid is a very important intermediate in metabolism. The compound is involved in the citric acid cycle for energy production within the cell.
Many experimental and studies have shown it plays a prominent role in life extension, anti-aging, blood sugar regulation, protect brain health, improved sleeping and energy etc.
- Life extension&Anti-aging
Oxaloacetic acid as a nutritional supplement,and could increase lifespan in animals. The research out of UCSD and UCLA in "Aging Cell" documents that excess oxaloacetate supplemented to C.Elegans,flys causes an increase in lifespan of 25%.Also, some related article strongly suggests that the molecular pathways activated by oxaloacetate supplementation are the same pathways as are activated in dietary restriction.The mechanism is the ability of oxaloacetate to mimic the calorie restricted metabolic state (but without the need to cut calories) and there is no side effect.
A famous brand-benaGene contains patented "Thermally Stabilized Oxaloacetate" and Vitamin C.Oxaloacetate is a natural energy molecule that is critical to human metabolism and proper cellular function.
- Blood Sugar Regulation
Some researchers from Japan isolated oxaloacetic acid was able to reduce blood sugar levels in mice. It was tested in humans and determined to be effective in a majority of participants with both two different types of diabetes. Later through infrared spectral analysis, and created a sodium-based form of oxaloacetic acid, they discovered that it significantly lowered blood sugar levels in both normal and diabetic animals.
- Other functions:
Anti-cancer & Anti-tumor
Protect brain health
Improving sleeping & energy
Maintenance weight
Cima Oxaloacetic acid（OAA）
Oxaloacetic acid,there are four ways to generation:
- Generated by phosphoenolpyruvate (PEP)
- Generated by Malic acid
- Generated by Pyruvic acid
- Generated by Aspartic acid
Cima Oxaloacetic acid, is generated by Aspartic acid through enzymatic catalytic under controlled temperature.It has the following typical characteristics:
- Thermal stability,safety to ship
- Enzymatic produce,high specificity
- Mass manufacturing,supply stable
- Reasonable price,professional services
Now with its developing, the oxaloacetic acid use as a supplement in energy production, brain-boosting, anti-cancer..... So the prospects are wonderful!
Oxaloacetic acid dosage
There is no recommendation for the dosage of oxaloacetic acid. However, the supplements containing stabilized oxaloacetic acid on the label shows that is100 mg each day in capsule form, usually combined with vitamin C and other natural ingredients in the market.
Oxaloacetic acid caution & storage
The storage stability is largely depends on the purity and the contaminants present in oxalacetic acid. It is unstable in solution,decomposing to pyruvate by decarboxylation over a period of hours (room temperature).Oxalacetic acid may decompose in solution even at 0°C.So oxalacetic acid is recommended to be stored and ship below 10°C, however lower quality materials and long term storage term require storage temperatures below -10°C.
Where to buy Oxaloacetic acid?
Cimasci offering oxaloacetic acid with high quality and good price.
Some similar products like PQQ,Pterostilbene, Resveratrol, Cycloastragenol, etc.
Contact:Wuxi Cima Sciecne Co,.Ltd
Email:amy.cheng@cimasci.com
